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Opportunistic pathogens
Germs that only become a problem when the balance is off. 6 chapters – expand
- Level:Intermediate Opportunistic pathogens Germs that are always there and only become a problem when the balance tips. AntibioticsAcid blockersMedicationProbioticsGut infectionsInflammationTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate After antibiotics: C. difficile and faecal transplants A germ that can take over after antibiotics, and a treatment that works better than any drug. AntibioticsFaecal transplantProbioticsDiarrhoeaGut infectionsBile acidsToxins and mould Established How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate Fungi in the gut: what is true about Candida Yeasts are part of the normal gut microbiota. When they are a problem and when they are not. AntibioticsGut infectionsTests and diagnostics Plausible How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Herxheimer reaction, die-off and toxins When feeling worse at the start of treatment is real, and when "detox" is used to explain away harm. Toxins and mouldAntibioticsGut infectionsParasitesProbiotics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Saccharomyces boulardii: the probiotic yeast Why a yeast survives antibiotics, what it is proven to help with, and when it can become dangerous. ProbioticsAntibioticsDiarrhoeaGut infections Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Gut and cancer: what the gut microbiota protects against, what harms, and why it matters in cancer treatment Fibre and its bacteria protect against colorectal cancer, while some bacteria damage the genome. Why colorectal cancer is rising in people under 50, which germs travel along in tumours, what Helicobacter has to do with stomach cancer, and why the gut microbiota helps decide whether immunotherapy works. FibreInflammationAntibioticsProbioticsTests and diagnosticsMouth and teethFaecal transplantBile acids Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.