Chapters
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Gut barrier
The gut lining as the border between gut contents and the body. 1 chapter – expand
- Level:Intermediate Butyrate and other short-chain fatty acids What gut bacteria make from fibre and what the body needs these substances for. Short-chain fatty acidsFibreInflammationPlant diversity Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
Microbial diversity
Why many different species keep the gut stable. 1 chapter – expand
- Level:Intermediate Carnivore and keto: less gas, but at what cost? Why many people feel less bloated on an all-meat or ketogenic diet, what this does to gut bacteria, and why experts do not recommend it for gut health. FibreShort-chain fatty acidsPlant diversityBloatingBody weight Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
Digestive function
Stomach acid, bile and enzymes as groundwork for the gut. 1 chapter – expand
- Level:Intermediate Oxalate, salicylate, lectins: hidden culprits or internet myth? Where these plant compounds really cause problems, such as kidney stones, after bowel surgery or with raw beans, and why lists against "oxalate dumping" and lectins tend to harm the gut. Toxins and mouldPlant diversityFibreMedication Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
Immune system and inflammation
The gut as the body's largest immune organ. 1 chapter – expand
- Level:Intermediate SCD, GAPS and the autoimmune protocol: what strict elimination diets can and cannot do Diets with long lists of forbidden foods promise to heal the gut. What studies show about SCD, GAPS and AIP, and why a short, structured test is different from months of avoidance. InflammationMediterranean dietFODMAPPlant diversity Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community