Chapters
Take the gut check and we will sort the chapters by relevance for you.
Immune system and inflammation
The gut as the body's largest immune organ. 4 chapters – expand
- Level:Expert Mast cells: alarm cells in the gut, histamine and the disputed MCAS Mast cells sit just beneath the gut lining and release histamine when alarmed. What they have to do with IBS and stress, and why mast cell activation syndrome is so often wrongly diagnosed. HistamineIBSStressAllergies Plausible How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Allergies and intolerances: how the gut learns to tolerate food Every day the gut has to tolerate foreign protein. How this tolerance develops, what role bacteria, stomach acid and skin play, and why many people feel allergic without being so. AllergiesProbioticsAcid blockersAntibioticsTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Skin and gut: what there is to the gut-skin axis Acne, rosacea, eczema, psoriasis: which links to the gut are proven, where a real disease is behind it, and where the hype begins. InflammationCoeliac disease and glutenProbioticsAllergiesAntibiotics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Beginner Dogs and cats: what pets do to your gut, immune system and nerves Living with animals means sharing microbes, dust and daily life with them. What that means for gut bacteria, allergies, inflammation and the vagus nerve, which of it is only an association, and where pets bring germs along too. AllergiesInflammationStressExerciseGut infectionsAntibiotic resistance Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.