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Well supported

Chapters that readers rate at 4 out of 5 stars or more on average for this question. An average only exists from 3 ratings. You can choose several.

Gut barrier

The gut lining as the border between gut contents and the body. 1 chapter – expand
  • Level:Beginner The gut barrier A layer of cells thinner than a hair separates the gut contents from the body. What keeps it tight. FibreAlcoholAdditivesCoeliac disease and glutenInflammationTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.

Microbial diversity

Why many different species keep the gut stable. 3 chapters – expand
  • Level:Beginner For everyone Your gut in ten minutes Who lives there, what do they do, and why is balance more important than individual germs? FibrePlant diversityFermented foodsAntibioticsExerciseTests and diagnostics Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
  • Level:Beginner Building microbial diversity Why many different species keep the gut stable and how to rebuild them after antibiotics. Plant diversityFermented foodsProbioticsAntibioticsFibre Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
  • Level:Beginner For everyone Big effect, small budget: low-cost measures for your gut What demonstrably helps the gut often costs almost nothing: slow breathing, cooled potatoes, potato starch from the supermarket, legumes, psyllium, kiwis, a stool in front of the toilet. An overview of how well each is supported, what it costs and where you can skip expensive detours. FibreExerciseStressPrebioticsFermented foodsConstipationBloatingShort-chain fatty acids Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.

Digestive function

Stomach acid, bile and enzymes as groundwork for the gut. 3 chapters – expand
  • Level:Beginner Constipation: more than too little fibre Kiwifruit, psyllium, pelvic floor and methane: what is behind sluggish digestion. ConstipationFibreExerciseMedication Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
  • Level:Beginner Diverticula, haemorrhoids and fissures: what can go wrong at the end of the gut Three common problems in the lower gut that people rarely talk about. Why nuts and seeds are fine with diverticula, why mild diverticulitis often heals without antibiotics, and what your phone on the toilet has to do with haemorrhoids. FibreConstipationInflammationAntibiotics Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
  • Level:Beginner Bloating and fullness: gas that will not move on Why the belly distends even though there is rarely too much gas – and what really helps. BloatingIBSFODMAPSweetenersFibreExercise Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community