Diverticula, haemorrhoids and fissures: what can go wrong at the end of the gut
Three common problems in the lower gut that people rarely talk about. Why nuts and seeds are fine with diverticula, why mild diverticulitis often heals without antibiotics, and what your phone on the toilet has to do with haemorrhoids.
How solid is the research? Trust score 4 of 5:Well supported
For fibre and against the nut myth there are large cohort studies and meta-analyses, for skipping antibiotics in mild diverticulitis two large randomised trials, for fissure ointments a Cochrane review. Toilet habits and sitz baths are less well supported.
Cause or consequence? Root cause 0 of 5:Purely a consequence
Diverticula, haemorrhoids and fissures come mainly from hard stool and long straining; with diverticula, age and genes also play a part. So they are consequences, but they cause symptoms themselves: fissures hurt, haemorrhoids bleed or itch, diverticula can become inflamed. They rarely trigger further gut problems.
Healthy state
The wall of the colon has weak spots where blood vessels pass through the muscle layer. There, the lining can bulge outwards, probably encouraged by high pressure with hard stools. These little pouches are called Diverticula Small pouches of the gut lining that bulge through weak spots in the colon wall. When they become inflamed, it is called diverticulitis. , and having them is diverticulosis. They are common, especially with age, and usually cause no symptoms: of more than 2,000 people whose colonoscopy showed diverticula, only about 4 per cent developed inflammation over eleven years.
Everyone has haemorrhoids. They are vascular cushions at the end of the rectum that act like a seal to help close the anus. Haemorrhoidal disease is only present when they swell, bleed, itch or protrude.
The skin of the anal canal is very sensitive. An inner sphincter keeps the anus closed involuntarily, an outer one can be controlled at will. During a bowel movement both relax, and soft, formed stool slides out without straining (see the pelvic floor chapter).
What all three problems have in common is that hard stools, heavy straining and long sitting raise the pressure. Fibre that makes stools soft and bulky is therefore the foundation for all three.
Disrupted state: causes and effects
When a diverticulum becomes inflamed, diverticulitis develops: usually pain in the lower left abdomen, often with fever, sometimes with nausea or changed bowel habits. In the uncomplicated form, the inflammation stays within the gut wall; in the complicated form, abscesses, fistulas or a perforation develop. The diagnosis is usually confirmed by CT. In one study, people under 50 had a higher risk of recurrence.
For a long time everyone with diverticulitis received antibiotics. Two large Randomised trial A study in which chance decides who gets the treatment and who does not, for comparison. This makes results particularly reliable. challenged this: in the Swedish AVOD trial (623 people) and the Dutch DIABOLO trial (528 people), a first uncomplicated diverticulitis healed just as well without antibiotics, with the same rates of complications and recurrence, even after two years. US gastroenterologists therefore now recommend antibiotics only selectively, but explicitly for people with weakened immunity. This is the doctor's decision, not yours: diverticulitis always needs to be seen by a doctor.
A persistent piece of advice is to avoid nuts, seeds, corn and popcorn with diverticula because they could get stuck in the pouches. A study of more than 47,000 men over 18 years found the opposite: those who ate nuts or popcorn at least twice a week tended to have diverticulitis less often, and there was no link with diverticular bleeding.
More fibre is associated with less diverticular disease. In a Meta-analysis An analysis that combines the results of several studies. It is only as good as the studies it includes. of five large cohort studies, the risk fell by about a quarter per 10 grams of fibre a day, most clearly for fibre from cereals and fruit.
Haemorrhoids cause problems when the cushions swell under pressure and the supporting tissue gives way: bright red blood on the paper, itching, seepage, a lump that comes out when straining. Long sitting on the toilet is considered a risk. In a US study of 125 people before colonoscopy, two thirds took their phone to the toilet; they sat longer, and phone use was linked to a 46 per cent higher risk of haemorrhoids. A Turkish study found no such link for phones, but did for sitting times over 20 minutes. What matters is probably the time, not the device.
An anal fissure is a small tear in the skin of the anal canal, usually after a hard stool. Typical is a sharp, burning pain during bowel movements that often lingers for a long time, and a little bright red blood. The pain makes the inner sphincter cramp, which reduces blood flow, the tear heals poorly, and fear of the next bowel movement makes people hold back stool. If a fissure lasts longer than about six weeks, it is considered chronic.
Important: blood from the anus is never automatically "just haemorrhoids". In people aged 50 and over who saw their GP with rectal bleeding, colorectal cancer was behind it in about 8 per cent of cases, according to a review. A colonoscopy is also often recommended after diverticulitis: in just under 2 per cent, colorectal cancer was hiding behind the picture, considerably more often in the complicated form.
Where it comes from and where it leads
The same symptoms can have different roots. This map shows what may be involved in this problem and what may follow from it.
Possible causes. Constipation, Supplements, Medication, Pelvic floor, Hormones & cycle, Methane & H₂S, Autoimmunity, POTS & connective tissue, Stress & sleep, SIBO, Gut immunity. Possible consequences. Abdominal pain, Food fear, Nutrient deficiency
- Possible causes
- This problem
- Possible consequences
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Move the mouse over a box: its connections are highlighted and everything else steps back.
Tap a box to highlight its connections. Tap it again to open the chapter.
Connections, not certainty: a link means “can”, not “must”. What applies to you is best clarified in a talk with your doctor.
What often helps
Lifestyle
Diet, exercise, sleep, social contact and dealing with stress.
- Fibre from cereals and fruit Wholegrains, oats, fruit and pulses make stools soft and lower the risk of diverticular disease in large studies. If you currently eat little, increase slowly over a few weeks and drink enough, otherwise you will get bloating. Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [1][2]
- Nuts, seeds and popcorn are allowed There is no reason to avoid them because of diverticula. In the large study of men, eating them more often tended to go with less diverticulitis. Professional societies now recommend an overall high-quality diet instead. Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [3][4]
- Short toilet visits, leave the phone outside Only go when you feel the urge, do not strain, and get up after a few minutes if nothing happens. A footstool makes emptying easier (see the pelvic floor chapter). The phone tempts you to sit for long. Plausible How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [5][6]
- Exercise, weight, not smoking To prevent recurrent diverticulitis, US gastroenterologists recommend a good diet, a normal weight, physical activity and not smoking. Avoid painkillers such as ibuprofen or diclofenac where possible unless prescribed. Genes play a role too; not every recurrence can be prevented. Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [4]
Natural supplements
Supplements do not replace a medical check-up. Discuss dosage and interactions with your doctor or pharmacist.
- Psyllium husk In a meta-analysis of seven trials of fibre supplements for haemorrhoids, the risk of persisting symptoms fell by 47 per cent and of bleeding by half. Fibre also helps with fissures because stools become softer. Start low and drink plenty. Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [7]
- Sitz baths: pleasant, little evidence Warm sitz baths are often recommended for fissures and haemorrhoids. In a small study after fissure surgery they eased burning but not pain. A few minutes in warm water without additives does no harm; avoid hot baths and irritating bath additives. Plausible How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [8][9]
Medical treatments
Information, not a treatment recommendation. Decide together with a doctor. Approval and availability differ from country to country.
- Uncomplicated diverticulitis: antibiotics not always needed In a first, CT-confirmed uncomplicated diverticulitis, the inflammation healed just as well without antibiotics in two large trials. Whether they are needed in an individual case is for your doctor to decide. With fever, severe pain, weakened immunity or complications they remain part of treatment. Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [10][11][12][4]
- Fissure: ointments that relax the sphincter Prescription ointments with nitroglycerin or calcium channel blockers (diltiazem, nifedipine) relax the cramped muscle. In a Cochrane review, nitroglycerin healed slightly more fissures than placebo (49 versus 36 per cent) and often causes headaches; the calcium channel blockers worked as well with fewer side effects. Botox is another option. Surgery heals most often but carries a small risk of incontinence. Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [13]
- Haemorrhoids: small procedures first If fibre and toilet habits do not help, rubber band ligation in the clinic can shrink the cushions. It is less painful than surgery; for markedly protruding haemorrhoids, surgery lasts longer. Over-the-counter ointments ease symptoms but do not remove the cause. Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [14]
- Always get blood checked Blood in or on the stool, dark blood or blood mixed with stool, changed bowel habits, weight loss or anaemia need to be examined by a doctor, especially from age 50. Even if you know you have haemorrhoids: they can hide another source of bleeding. Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. [15][16]
In the mood for something completely different? Another one, at random
How we rate the evidence
- Trust score 5 of 5:Established
- Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies.
- Trust score 4 of 5:Well supported
- Several randomised studies in humans with largely consistent results.
- Trust score 3 of 5:Promising
- Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies.
- Trust score 2 of 5:Plausible
- Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms.
- Trust score 1 of 5:Experimental
- Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
Sources
- Aune et al. 2020: Dietary fibre and diverticular disease, meta-analysis (European Journal of Nutrition)
- Crowe et al. 2014: Fibre sources and diverticular disease in 690,000 women (Gut)
- Strate et al. 2008: Nuts, corn, popcorn and diverticular disease, cohort of 47,228 men (JAMA)
- Peery et al. 2021: AGA clinical practice update on managing diverticulitis (Gastroenterology)
- Ramprasad et al. 2025: Smartphone use on the toilet and haemorrhoids (PLOS ONE)
- Yazkan et al. 2025: Toilet behaviours and anorectal disease, cross-sectional study (Frontiers in Surgery)
- Alonso-Coello et al. 2006: Fibre for haemorrhoids, meta-analysis (American Journal of Gastroenterology)
- Tejirian & Abbas 2005: Sitz baths, review of the evidence (Diseases of the Colon & Rectum)
- Gupta 2007: Warm sitz baths after fissure surgery, randomised trial (World Journal of Surgery)
- Chabok et al. 2012: AVOD trial, antibiotics in uncomplicated diverticulitis (British Journal of Surgery)
- Daniels et al. 2017: DIABOLO trial, observation instead of antibiotics in uncomplicated diverticulitis (British Journal of Surgery)
- van Dijk et al. 2018: DIABOLO trial, two-year results (American Journal of Gastroenterology)
- Nelson et al. 2012: Non-surgical therapy for anal fissure, Cochrane review
- Shanmugam et al. 2005: Rubber band ligation versus surgery for haemorrhoids, Cochrane review
- Astin et al. 2011: Diagnostic value of symptoms for colorectal cancer in primary care, systematic review (British Journal of General Practice)
- Meyer et al. 2019: Colorectal cancer in acute diverticulitis, meta-analysis (Clinical Gastroenterology and Hepatology)
- Shahedi et al. 2013: Long-term risk of diverticulitis in diverticulosis (Clinical Gastroenterology and Hepatology)
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