Chapters
Take the gut check and we will sort the chapters by relevance for you.
Gut barrier
The gut lining as the border between gut contents and the body. 1 chapter – expand
- Level:Intermediate Gut and endurance sport: runner’s gut, cramps and what helps During long, hard sessions the gut gets less blood, briefly becomes leakier and digests less well. Why runners are hit more often, what heat and ibuprofen have to do with it, and why the gut can be trained. ExerciseDiarrhoeaFODMAPMedicationNutrientsBloating Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
Gut-brain axis
How stress, sleep and nerves steer digestion. 1 chapter – expand
- Level:Intermediate Fear of food: when your list of safe foods keeps shrinking How gut symptoms can tip into fear of eating, ARFID or orthorexia, why unintended weight loss is a warning sign, and how to find your way back to a varied diet. PsychotherapyBody weightIBSFODMAP Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
Digestive function
Stomach acid, bile and enzymes as groundwork for the gut. 1 chapter – expand
- Level:Intermediate Digestive enzymes from mouth to colon: who breaks down what Saliva, stomach, pancreas, gut wall and bacteria each contribute their own enzymes. A map of where each enzyme works, and what happens when one is missing. FODMAPBloatingCoeliac disease and glutenTests and diagnostics Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
Small intestine colonisation
When bacteria grow where few belong. 3 chapters – expand
- Level:Intermediate When the small intestine is too densely colonised Bacteria in the wrong place: why fibre can then become a problem. BloatingFODMAPAntibioticsIBSConstipationBile acidsTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Doing low-FODMAP right The best-studied diet for bloating, and why it is only meant to be temporary. FODMAPBloatingIBS Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate Prebiotics that build up gently Why some fibres cause bloating and others feed the gut microbiota gently. FibreBloatingFODMAPShort-chain fatty acidsIBSPrebiotics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
Immune system and inflammation
The gut as the body's largest immune organ. 1 chapter – expand
- Level:Intermediate SCD, GAPS and the autoimmune protocol: what strict elimination diets can and cannot do Diets with long lists of forbidden foods promise to heal the gut. What studies show about SCD, GAPS and AIP, and why a short, structured test is different from months of avoidance. InflammationMediterranean dietFODMAPPlant diversity Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community