Chapters
Take the gut check and we will sort the chapters by relevance for you.
Gut barrier
The gut lining as the border between gut contents and the body. 1 chapter – expand
- Level:Intermediate Gut and endurance sport: runner’s gut, cramps and what helps During long, hard sessions the gut gets less blood, briefly becomes leakier and digests less well. Why runners are hit more often, what heat and ibuprofen have to do with it, and why the gut can be trained. ExerciseDiarrhoeaFODMAPMedicationNutrientsBloating Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
Microbial diversity
Why many different species keep the gut stable. 1 chapter – expand
- Level:Intermediate Carnivore and keto: less gas, but at what cost? Why many people feel less bloated on an all-meat or ketogenic diet, what this does to gut bacteria, and why experts do not recommend it for gut health. FibreShort-chain fatty acidsPlant diversityBloatingBody weight Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
Digestive function
Stomach acid, bile and enzymes as groundwork for the gut. 4 chapters – expand
- Level:Intermediate Stomach acid, bile and enzymes The groundwork in the stomach and small intestine determines what reaches the large intestine. Acid blockersMedicationBile acidsAlcoholBloatingTests and diagnostics Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate Sensitive stomach: fullness, upper abdominal pain and Helicobacter What is behind upper abdominal symptoms when the endoscopy is normal, why the Helicobacter test comes first and what else helps. BloatingIBSAcid blockersTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate Digestive enzymes from mouth to colon: who breaks down what Saliva, stomach, pancreas, gut wall and bacteria each contribute their own enzymes. A map of where each enzyme works, and what happens when one is missing. FODMAPBloatingCoeliac disease and glutenTests and diagnostics Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate Gastroparesis: when the stomach empties too slowly Nausea, vomiting, feeling full after a few bites: in gastroparesis, food stays in the stomach too long. Why it can hardly be separated from functional dyspepsia, what diabetes, viruses and weight-loss injections have to do with it, and what helps. BloatingMedicationBlood sugarTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
Small intestine colonisation
When bacteria grow where few belong. 3 chapters – expand
- Level:Intermediate When the small intestine is too densely colonised Bacteria in the wrong place: why fibre can then become a problem. BloatingFODMAPAntibioticsIBSConstipationBile acidsTests and diagnostics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community
- Level:Intermediate Doing low-FODMAP right The best-studied diet for bloating, and why it is only meant to be temporary. FODMAPBloatingIBS Well supported How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open.
- Level:Intermediate Prebiotics that build up gently Why some fibres cause bloating and others feed the gut microbiota gently. FibreBloatingFODMAPShort-chain fatty acidsIBSPrebiotics Promising How we rate the evidence Established Recommended in medical guidelines or supported by several consistent meta-analyses of randomised human studies. Well supported Several randomised studies in humans with largely consistent results. Promising Single randomised or controlled studies in humans, not yet independently confirmed — or many consistent observational studies. Plausible Two cases: first observational or pilot studies with small samples — or a settled basis that is not in dispute, such as movement, sleep or meal pauses. But not tested in humans for symptoms. Experimental Barely studied in humans. Mainly lab and animal studies or theoretical reasoning; whether it helps is open. Community